Anxiety in youth at clinical high-risk for psychosis: A two-year follow-up

Individuals at clinical high-risk (CHR) for psychosis comprise a heterogeneous group with respect to symptoms and functioning both at presentation and at a later outcome. Even those who do not develop psychosis are troubled by comorbid symptoms and poor functioning (Addington et al., 2018). A recent commentary in this journal (Woods et al., 2021) reports on several papers demonstrating that longitudinally CHR individuals are troubled by unresolved attenuated psychotic symptoms (APS), functional deficits, persistent negative symptoms, and depression. It is argued that before adequate treatments can be developed, a specific core battery of outcome variables is needed.