Response by Falkstedt et al to Letters Regarding Article, 'Cannabis, Tobacco, Alcohol Use, and the Risk of Early Stroke: A Population-Based Cohort Study Among 45 000 Swedish Men'

First, we express our appreciation of the comments on our study by Kawada and by Behrouz and Aachi. We seem to agree on the value of studies on this matter. In both letters, the authors highlight that cannabis use in our study (as well as tobacco and alcohol use) could be measured only in late adolescence and, as a result, little is known about its prevalence later, when cases of stroke occur. Therefore, the authors suspect that our analysis could have missed an association between cannabis use in adulthood and stroke events. This cannot be ruled out, which we touched on in the discussion of our results. However, some prevalence of cannabis use in adulthood is still expected, and we think that in such cases, it was generally preceded by teenage use. With regard to tobacco smoking, >90% of those who were smokers later in life already smoked before …