Inhibition of Acid Sphingomyelinase Blocks Infection with SARS-CoV-2

Authors :: Alexander Carpinteiro
Michael J. Edwards
Markus Hoffmann
Georg Kochs
Barbara Gripp
Sebastian Weigang
Constantin Adams
Elisa Carpinteiro
Anne Gulbins
Simone Keitsch
Carolin Sehl
Matthias Soddemann
Barbara Wilker
Markus Kamler
Thomas Bertsch
Karl S. Lang
Sameer Patel
Gregory C. Wilson
Silke Walter
Hartmut Hengel
Stefan Pöhlmann
Philipp Lang
Johannes Kornhuber
Katrin Anne Becker
Syed A. Ahmad
Klaus Fassbender
Erich Gulbins
Source :: SSRN Electronic Journal.
Publication Year :: 2020
Publisher :: Elsevier BV, 2020.
Abstract: We have previously shown that the acid sphingomyelinase/ceramide system plays an important role in bacterial and viral infections Pharmacological inhibition of

Subjects :: Ceramide
chemistry.chemical_compound
2019-20 coronavirus outbreak
chemistry
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
medicine
Acid sphingomyelinase
Virology
medicine.drug

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