Back to Search
Start Over
Improved Synthesis of Vitamin K1
- Source :
- ChemInform. 34
- Publication Year :
- 2003
- Publisher :
- Wiley, 2003.
-
Abstract
- With (E/Z)-isomeric phytyl halides as side-chain materials, vitamin K 1 is synthesized via a Diels–Alder reaction to activate the free bridgehead hydrogen of 3 for the alkylation and a retro-Diels–Alder reaction to eliminate cyclopentadiene from 2 in a high yield, in which the configuration of the double bond in the phytyl side-chain is retained.
Details
- ISSN :
- 15222667 and 09317597
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........15cf6bbab9d36f67fffbf0c91585418a