Up-regulation of natural killer (NK) cell activating receptors and increase in NK mediated cytotoxicity using interleukin-15 in patients with newly diagnosed acute myeloid leukemia (AML)

Authors :: Theresa L. Whiteside
Kenneth A. Foon
Miroslaw J. Szczepanski
Marta Szajnik
Michael Boyiadzis
Ann Welsh
Malgorzata Czystowska
Source :: Journal of Clinical Oncology. 26:3076-3076
Publication Year :: 2008
Publisher :: American Society of Clinical Oncology (ASCO), 2008.
Abstract: 3076 Background: NK cell cytotoxicity is tightly controlled through a balance of signals from the functionally opposing activating and inhibitory receptors found on each cell. Interleukin-15 (IL-15...

Subjects :: Cancer Research
Lymphokine-activated killer cell
business.industry
Cell
Myeloid leukemia
Interleukin 21
medicine.anatomical_structure
Oncology
Downregulation and upregulation
Interleukin 15
Immunology
Medicine
In patient
business
Cytotoxicity

Full Text Access

Tools