Comorbidites and uncontrolled asthma in a ‘real life’ population study

Objective: To determine the comorbidities associated to a poor control of asthma. Methods: Retrospective population-based cohort study including 2000 asthmatic patients obtained by simple-random-sampling. Asthma exacerbations were defined as episodes requiring at least oral corticosteroid. The excessive use of rescue medication was determined by the ‘asthma medication ratio’, being the ratio Results: 7.9% of patients suffered from at least one moderate exacerbation during the monitoring year. The 15.1% of the patients scored Conclusions: Psychiatric history, cardiovascular disease and chronic renal failure were independently associated to a worse control of asthma. The association for chronic renal failure was especially strong and deserve further consideration.