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Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices
- Source :
- Soft Matter. 6:4715
- Publication Year :
- 2010
- Publisher :
- Royal Society of Chemistry (RSC), 2010.
-
Abstract
- A new family of elastomeric nanocomposites has been developed from a soft elastomer poly(glycerol sebacate, PGS) and nanoparticles of Bioglass®. The new nanocomposites have been characterised in terms of materials science and evaluated for their potential clinical applications as cell delivery vehicles and cardiac support devices in the heart patch strategy. The addition of alkaline Bioglass® effectively counteracts the acidity caused by the degradation of PGS without severely compromising the compliance of PGS. As a result, the newly developed PGSānanoBioglass (
- Subjects :
- musculoskeletal diseases
endocrine system
Nanocomposite
Materials science
Polymer network
Biocompatibility
urogenital system
Nanoparticle
Nanotechnology
General Chemistry
Condensed Matter Physics
Elastomer
Cell delivery
Cardiac support
carbohydrates (lipids)
lipids (amino acids, peptides, and proteins)
Biomedical engineering
Subjects
Details
- ISSN :
- 17446848 and 1744683X
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Soft Matter
- Accession number :
- edsair.doi...........1439034ae5c1fb7e71196bc0ee728bd8