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Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices

Authors :
Liyu Jin
John M. Haynes
Colin W. Pouton
David A. Elliott
Wayne D. Cook
Qizhi Chen
Edouard G. Stanley
Wendelin J. Stark
Dirk Mohn
Ebba Louise Lagerqvist
Nicholas Boyd
Andrew G. Elefanty
Source :
Soft Matter. 6:4715
Publication Year :
2010
Publisher :
Royal Society of Chemistry (RSC), 2010.

Abstract

A new family of elastomeric nanocomposites has been developed from a soft elastomer poly(glycerol sebacate, PGS) and nanoparticles of Bioglass®. The new nanocomposites have been characterised in terms of materials science and evaluated for their potential clinical applications as cell delivery vehicles and cardiac support devices in the heart patch strategy. The addition of alkaline Bioglass® effectively counteracts the acidity caused by the degradation of PGS without severely compromising the compliance of PGS. As a result, the newly developed PGSā€“nanoBioglass (

Details

ISSN :
17446848 and 1744683X
Volume :
6
Database :
OpenAIRE
Journal :
Soft Matter
Accession number :
edsair.doi...........1439034ae5c1fb7e71196bc0ee728bd8