Ganglioside in Meningiomen und Hirnh�uten

The ganglioside concentrations and the ganglioside patterns were investigated in 18 meningiomas of different histological type and in the meninges. The ganglioside concentration in the meningiomas ranged from 0.16 to 1.63 mg ganglioside N-acetylneuraminic acid per gram dry weight (mean 0.68 mg/g). The gangliosides GM3, GD3 and GD1a were found to be the major ganglioside fractions of the meningiomas. In the endotheliomatous meningiomas, on teh average, the percentage of GM3 was higher, and the percentage of GD3 lower than in the endotheliomatous-fibromatous tumours. However, none of the individual ganglioside patterns observed seemed to be specific of a certain histological type.