A new preparative method and some chemical properties of 4-R-furazan-3-carboxylic acid amidrazones

An alternative method has been developed for the preparation of 4-R-furazan-3-carboxylic acid amidrazones (R = OMe, NH2, substituted amino group) by reductive opening of 1,2,4-oxadiazole ring in 4-R derivatives of (1,2,4-oxadiazol-3-yl)furazans by the action of hydrazine. The starting 1,2,4-oxadiazoles were synthesized from 4-aminofurazan-3-carboxylic acid amidoxime. Some chemical properties of the obtained compounds were studied.