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Synthesis of sialic acid through aldol condensation of glucose with oxalacetic acid
- Source :
- Tetrahedron Letters. 33:325-328
- Publication Year :
- 1992
- Publisher :
- Elsevier BV, 1992.
-
Abstract
- N-Acetylneuramimic acid (sialic acid) 1 was synthesized through relatively short steps from d -glucose via a key intermediate 1,5-lactone derivative obtained from the pyranose isomer of the aldol condensation products of d -glucose with oxalacetic acid.
Details
- ISSN :
- 00404039
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........134bc99c2160cf5505490dc900d83a94
- Full Text :
- https://doi.org/10.1016/s0040-4039(00)74122-0