660: Screening of ELX-02 readthrough effect by forskolin-induced swelling assay in CFTR nonsense mutation–bearing organoids as predictive test for clinical trial patient stratification

Authors :: Sylvia F. Boj
Sylvia W.F. Suen
Matthew M. Goddeeris
M. Bierlaagh
Anabela S. Ramalho
Annelotte M. Vonk
Françoise Vermeulen
J. Pott
Daniel K. Crawford
Iris A.L. Silva
K. De Boeck
Margarida D. Amaral
C.K. van der Ent
Jeffrey M. Beekman
Source :: Journal of Cystic Fibrosis. 20:S313
Publication Year :: 2021
Publisher :: Elsevier BV, 2021.

Subjects :: Pulmonary and Respiratory Medicine
Forskolin
business.industry
Nonsense mutation
medicine.disease
Cystic fibrosis
Clinical trial
chemistry.chemical_compound
chemistry
Pediatrics, Perinatology and Child Health
Organoid
Cancer research
Medicine
Swelling
medicine.symptom
business
Predictive testing
Patient stratification

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