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Blainvillea rhomboidea: constituintes químicos e atividade citotóxica

Authors :
Hélcio Silva
Letícia Veras Costa Lotufo
Regina Ferreira Gomes
Felipe A. R. Rodrigues
Cláudia Pessoa
Manoel Odorico de Moraes
Jane R. Albuquerque
L. Pessoa
Maria Rose
Source :
Química Nova. 33:1122-1125
Publication Year :
2010
Publisher :
FapUNIFESP (SciELO), 2010.

Abstract

the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methylethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (1H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity.

Details

ISSN :
01004042
Volume :
33
Database :
OpenAIRE
Journal :
Química Nova
Accession number :
edsair.doi...........1197488070c59787fea989282b18c9b9