Role of Laboratory Parameters in Preoperatively Predicting Perforated Appendicitis

Acute appendicitis is one of the most common pediatric surgical emergencies. Herewith we present our study to determine the correlation of preoperative laboratory investigations with intraoperative findings and histopathological report in children with appendicitis. A case series analysis of 60 patients undergoing appendicectomy was performed at the Department of Pediatric Surgery in All India Institute of Medical Sciences Jodhpur India from July 2018 to July 2019. Historic records were analyzed. Parameters studied were age, gender, duration of symptoms, total leucocyte counts and C-reactive protein, ultrasonography, intraoperative findings, placement of drain in perforated cases, postoperative duration of antibiotics, and hospital stay. We compared the values of total leucocyte counts and C-reactive protein in perforated and non-perforated cases. Histopathological report of the specimens was retrieved. The mean age of the patients was 11.23 years (range 2–18 years) with a male preponderance of 2:1. The mean total leucocyte count was 16,772 cells/mm3 in the perforated group which was significantly higher than the non-perforated group 10,872cells/mm3 (p value