ChemInform Abstract: Regioselective Alkylation of 4,6-Bis(methylthio)-1H-pyrazolo(3,4-d)pyrimidine

Reaction of 4,6-bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine with alkyl halides in the presence of sodium hydride produces predominantly 2-alkyl-4,6-bis(methylthio)-2H-pyrazolo[3,4-d]pyrimidines in good yields