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Incretin-Based Therapies for the Treatment of Type 2 Diabetes: Evaluation of the Risks and Benefits
- Publication Year :
- 2010
- Publisher :
- The University of North Carolina at Chapel Hill University Libraries, 2010.
-
Abstract
- Limited evidence suggests that GLP-I may also preserve ventricular function and improve outcomes in human subjects with heart failure or myocardial infarction (11,12). [...] both exenatide and liraglutide reduce blood pressure, body weight, and plasma lipid profiles in subjects with type 2 diabetes (13), raising the hope that longterm treatment with these agents may reduce the incidence of cardiovascular events.\n However, two safety issues have been raised - pancreatitis and medullary carcinoma of the thyroid.
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........0f495f2f34a32a34ee69a8bc32caa34a
- Full Text :
- https://doi.org/10.17615/kj4b-d081