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Determination of ochratoxin a in beer by high-performance liquid chromatography

Authors :
Markus Herderich
P. Degelmann
Hans-Ulrich Humpf
M. Becker
Source :
Chromatographia. 49:543-546
Publication Year :
1999
Publisher :
Springer Science and Business Media LLC, 1999.

Abstract

Ochratoxin A (OTA) is a nephrotoxic and nephrocacinogenic mycotoxin commonly produced by several ubiquitousAspergillus andPenicillium species. OTA is found predominantly in cereals and derived products, and therefore OTA may be transferred into beer from contaminated grain. Thirty-five samples of German beers were analyzed: OTA was extracted with toluene and purified by solid phase extraction using silica cartridges. OTA was determined by high-performance liquid chromatography with fluorescence detection. Since of fluorescence detection is not specific in this instance, the beer samples were also analyzed by high-performance liquid chromatography electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS). OTA levels in the range of 0.1–0.2 μg L−1 were found in 9 beer samples, 21 samples contained trace amounts of OTA (

Details

ISSN :
16121112 and 00095893
Volume :
49
Database :
OpenAIRE
Journal :
Chromatographia
Accession number :
edsair.doi...........0e5cbda8bf3dd1040759087ff386c7b1
Full Text :
https://doi.org/10.1007/bf02467756