Chiral Spiro Phosphoric Acid-Catalyzed Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions

Authors :: Zi-Qi Li
Xiao-Song Xue
Mao-Lin Li
Biying Zhou
Qi-Lin Zhou
Yi-Pan Li
Shou-Fei Zhu
Source :: ACS Catalysis. 9:6522-6529
Publication Year :: 2019
Publisher :: American Chemical Society (ACS), 2019.
Abstract: Asymmetric Friedel–Crafts conjugate addition reactions that generate an α-chiral center are challenging because the configuration-determining step is a proton-transfer reaction of a highly active e...

Subjects :: Addition reaction
010405 organic chemistry
Chemistry
Enantioselective synthesis
Protonation
General Chemistry
010402 general chemistry
01 natural sciences
Medicinal chemistry
Catalysis
0104 chemical sciences
chemistry.chemical_compound
Nuclear Experiment
Phosphoric acid
Friedel–Crafts reaction
Conjugate

Full Text Access

Tools