Back to Search
Start Over
Su1286 Differences Between Community and Academic Cohorts of Patients With Chronic Hepatitis B (CHB) in the Development of Hepatocellular Carcinoma (HCC)
- Source :
- Gastroenterology. 144:S-448
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- G A A b st ra ct s CI = 19%-27%) for patients receiving only supportive care, 39% (95% CI = 32%-46%) for those receiving liver-directed palliative therapy, 61% (95%CI = 51%-70%) for those undergoing partial hepatectomy, and 77% (95% CI = 71%-82%) for those having a liver transplantation. In multivariate analysis (Table), independent predictors for improved survival were non-White/non-Black race, palliative as well as surgical treatment. Independent predictors for poorer survival were age older than 65 and Black race (compared toWhites). Conclusions: In spite of improved opportunity for both effective palliative and curative therapies in the recent years, almost half of patients meeting Milan criteria are still not undergoing any therapy. In addition to assessing the efficacy and survival impact of current therapies, it is also important to focus on why so many patients diagnosed with HCC are not undergoing any treatment and reasons for continued existence of racial disparities. Early diagnosis through better screening protocols together with patient and physician education is crucial to achieve better outcomes. Multivariate Cox Proportional Hazards Model Assessing Factors Associated with Survival
- Subjects :
- medicine.medical_specialty
Multivariate analysis
Hepatology
Proportional hazards model
business.industry
medicine.medical_treatment
Gastroenterology
Physician education
Milan criteria
Liver transplantation
medicine.disease
Palliative Therapy
Chronic hepatitis
Hepatocellular carcinoma
Internal medicine
medicine
business
Subjects
Details
- ISSN :
- 00165085
- Volume :
- 144
- Database :
- OpenAIRE
- Journal :
- Gastroenterology
- Accession number :
- edsair.doi...........0c1750ee87d2eeada3a32880324f1855
- Full Text :
- https://doi.org/10.1016/s0016-5085(13)61653-4