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The Cytotoxic Activity of Diterpenoids fromIsodonspecies
- Source :
- Natural Product Communications. 7:1934578X1200700
- Publication Year :
- 2012
- Publisher :
- SAGE Publications, 2012.
-
Abstract
- Fifteen Isodon diterpenoids (1–15) were evaluated for their cytotoxic activity against HeLa and HL-60 human cancer cell lines, and against murine vincristine (VCR)-resistant P388 cells. Kamebanin (14) showed efficient cytotoxic activity against HeLa and HL-60 cells. In addition, although dihydroenmein (2) and trichorabdal B (7) were inactive against several tested cell types, they were found to have cytotoxic-enhancing activity of VCR against VCR-resistant P388 cells.
Details
- ISSN :
- 15559475 and 1934578X
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Natural Product Communications
- Accession number :
- edsair.doi...........0bd49270a6aed7d525e645b979ef2f57