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COVID-19 Epigenetics and Implications for Public Health

Authors :
Dhrubajyoti Chattopadhyay
Amit Kumar Mandal
Ahmet Kati
Gulsen Meral
Verda Tunaligil
Source :
Coronaviruses. 2:235-240
Publication Year :
2021
Publisher :
Bentham Science Publishers Ltd., 2021.

Abstract

Background: COVID-19 debilitated communities globally in varying complexities and capacities in recent months. Objective: The epigenetic changes in the COVID-19 patients were discussed in this article to explore various processes contributing to disease severity and elevation of risk due to infection. Result & Conclusion: The COVID-19 disease is observed to be the most severe in the 65 and-higher-age group with pre-existing chronic conditions. This observational study is a nonexperimental empirical investigation of the outcomes of COVID-19 in different patient groups. Results are promising for conducting clinical trials with intervention groups. To ultimately succeed in disease prevention, researchers and clinicians must integrate epigenetic mechanisms to generate valid prescriptions for global well-being. Methods: Percentages of hospitalization, with and without intensive care, in the presence of diseases with increased ACE2 expression, were compared, based on the best available data. Further analysis compared two different age groups, 19-64 and ≥65 years of age.

Details

ISSN :
26667967
Volume :
2
Database :
OpenAIRE
Journal :
Coronaviruses
Accession number :
edsair.doi...........0a8665ed039f870dd46ab454bcbc0489
Full Text :
https://doi.org/10.2174/2666796701999201005212515