Case Study: Development of Acetabular Socket Prototype

In some of the preceding chapters, the processing and biocompatibility property are discussed with a focus on ‘lab-scale’ research of designing new biomaterials. The translation of bench to bedside requires the fabrication of biomedical device prototype based on the lab-scale tested biomaterials. While addressing this aspect, this chapter and ZrO2—toughened Al2O3 reports design and development of the compression molded high density polyethylene (HDPE)-based biocompatible acetabular socket with 20 wt% hydroxyapatite (HA) and 20 wt% alumina (Al2O3) ceramic fillers for the total hip joint replacement applications. This new implant material can be used either for non-cemented socket or as a liner for a metal back porous coated cup. This is more relevant as the total hip joint replacement (THR) arthroplasty has reduced pain clinically and tremendously improved the quality of life for millions. In the context of a growing need to develop patient-specific biomedical devices, this chapter describes some physical properties and more importantly 3D microstructural characterization using micro-computed tomography.