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Improved outcomes with oral tongue squamous cell carcinoma in Finland

Authors :
Alhadi Almangush
Aaro Haapaniemi
Reidar Grénman
Antti Mäkitie
Jussi Laranne
Matti Pukkila
Tuula Salo
Rayan Mroueh
Source :
Head & Neck. 39:1306-1312
Publication Year :
2017
Publisher :
Wiley, 2017.

Abstract

Background Incidence rates for oral tongue squamous cell carcinoma (SCC) are steadily rising worldwide. Methods All patients diagnosed with primary oral tongue SCC at the 5 university hospitals in Finland from 2005 to 2009 were studied. The mean follow-up time was 43 months (median, 54 months; range, 0–111 months). Results Three hundred sixty patients with primary oral tongue SCC were identified. Treatment with curative intent was provided for 328 patients (91%). The 5-year disease-specific survival (DSS) rates were as follows: stage I 87%; stage II 73%; stage III 69%; and stage IV 51%. The 5-year recurrence-free survival in general has improved from 47% in our previous published series (1995–1999) to 65% in the current series (p < .001). Conclusion The outcome of oral tongue SCC has significantly improved in Finland. However, the relatively high number of disease recurrences in patients with stage I and II disease, when compared with patients with stage III and IV disease, calls for an investigation of new treatment approaches. © 2017 Wiley Periodicals, Inc. Head Neck, 2017

Details

ISSN :
10433074
Volume :
39
Database :
OpenAIRE
Journal :
Head & Neck
Accession number :
edsair.doi...........0998a8feb954f3e10ca650aeff99fef0
Full Text :
https://doi.org/10.1002/hed.24744