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Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours
- Source :
- Xenobiotica. 50:793-804
- Publication Year :
- 2019
- Publisher :
- Informa UK Limited, 2019.
-
Abstract
- The disposition and metabolism of prexasertib, a CHK-1 inhibitor was characterised over a 120 h period following a single 170-mg intravenous dose of [14C]prexasertib (50 µCi) to 6 patients with adv...
- Subjects :
- Pharmacology
Intravenous dose
medicine.medical_specialty
business.industry
Health, Toxicology and Mutagenesis
Oxidative deamination
General Medicine
Disposition
Metabolism
Toxicology
030226 pharmacology & pharmacy
Biochemistry
Gastroenterology
Excretion
03 medical and health sciences
0302 clinical medicine
030220 oncology & carcinogenesis
Internal medicine
Medicine
In patient
business
Subjects
Details
- ISSN :
- 13665928 and 00498254
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Xenobiotica
- Accession number :
- edsair.doi...........0896a36e4159007be6f88d05abf8fcf5
- Full Text :
- https://doi.org/10.1080/00498254.2019.1702736