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Difficulties in diagnosing atypical variants of Alzheimer’s disease
- Source :
- Russian neurological journal. 26:16-23
- Publication Year :
- 2021
- Publisher :
- Medical Informational Agency Publishers, 2021.
-
Abstract
- Alzheimer’s disease (AD) is the most common cause of dementia in the population. Late onset AD has a classic clinical picture with short-term memory deficit, apraxia and agnosia. Patients with early-onset AD may have an atypical clinical picture which complicates diagnosis. Atypical AD variants include the logopenic variant of primary progressive aphasia, posterior cortical atrophy, behavioral, biparietal, and cortico-basal variants. These variants have pathomorphological signs similar to classical AD, but at an early stage they are characterized by focal atrophy which explains their clinical polymorphism. This article provides a review of the current literature on atypical types of AD and presents a clinical case of a 62-year-old patient in whom the disease debuted with prosopagnosia due to focal atrophy of the temporo-occipital regions of the non-dominant hemisphere.
- Subjects :
- education.field_of_study
Pediatrics
medicine.medical_specialty
business.industry
Population
Posterior cortical atrophy
Late onset
Disease
medicine.disease
Apraxia
Primary progressive aphasia
Psychiatry and Mental health
Neurology
Agnosia
medicine
Dementia
Neurology (clinical)
medicine.symptom
education
business
Subjects
Details
- ISSN :
- 26867192 and 26587947
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Russian neurological journal
- Accession number :
- edsair.doi...........08169ee22a9531c12dcaf5a1d4ff646c
- Full Text :
- https://doi.org/10.30629/2658-7947-2021-26-5-16-23