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Optimization of the Manufacturing Route to PF-610355 (2): Synthesis of the API

Authors :
Stéphane Content
Thomas Dupont
Nicolas M. Fédou
Radoslav Penchev
Julian D. Smith
Flavien Susanne
Christopher Stoneley
Steven J. R. Twiddle
Source :
Organic Process Research & Development. 17:202-212
Publication Year :
2013
Publisher :
American Chemical Society (ACS), 2013.

Abstract

PF-610355 is a novel inhaled β-2 adrenoreceptor agonist. Process development of the final intermediate and the API are discussed with emphasis on the control of physical properties and subsequent i...

Details

ISSN :
1520586X and 10836160
Volume :
17
Database :
OpenAIRE
Journal :
Organic Process Research & Development
Accession number :
edsair.doi...........07da42fe99aa526dad4c9b561279821b
Full Text :
https://doi.org/10.1021/op300342y