Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (CCGA) study

Authors :: José Baselga
Minetta C. Liu
John F. Beausang
Samuel Gross
Ling Shen
Nan Zhang
Richard Thomas Williams
Oliver Venn
Arash Jamshidi
Geoffrey R. Oxnard
Charles Swanton
Timothy J. Yeatman
Alex Aravanis
Tara Maddala
Anne-Renee Hartman
Michael V. Seiden
Darya Filippova
Kelly L. Bolton
Anton Valouev
Earl Hubbell
Source :: Journal of Clinical Oncology. 36:12003-12003
Publication Year :: 2018
Publisher :: American Society of Clinical Oncology (ASCO), 2018.
Abstract: 12003Background: CHIP is defined by the presence of age-dependent acquired mutations in hematopoietic progenitor cells and has been reported to occur in up to 30% of individuals 60-70 years of age....

Subjects :: 0301 basic medicine
Cancer Research
business.industry
Clonal hematopoiesis
Exploratory analysis
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Oncology
030220 oncology & carcinogenesis
Cancer genome
Cancer research
Hematopoietic progenitor cells
Medicine
Indeterminate
business
Ultra sensitive

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