Optimization of dihydrosphingomyelin/cholesterol mol ratio in topotecan-loaded liposomes to enhance drug retention and plasma half-life by understanding physicochemical and thermodynamic properties of the lipid membrane

Authors :: Noriyuki Kasagi
Issei Doi
Jun Nakabayashi
Kengo Saito
Akiko Tadakuma
Nanae Muraki
Ritsuko Hori
Toshifumi Kimura
Ken Okada
Naoki Yamada
Keiko Makita-Suzuki
Hiroki Tanisaka
Susumu Shimoyama
Mikinaga Mori
Source :: Journal of Molecular Structure. 1283:135333
Publication Year :: 2023
Publisher :: Elsevier BV, 2023.

Subjects :: Inorganic Chemistry
Organic Chemistry
Spectroscopy
Analytical Chemistry

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