The first total synthesis of a bioactive metabolite, a spirobenzofuran isolated from the fungi Acremonium sp. HKI 0230

Authors :: B. Vasantha Lakshmi
Adusumilli Srikrishna
Source :: Tetrahedron Letters. 46:7029-7031
Publication Year :: 2005
Publisher :: Elsevier BV, 2005.
Abstract: The first total synthesis of a bioactive metabolite, isolated from the fungi Acremonium sp. HKI 0230, containing a cyclopentaspirobenzofuran carbon framework, employing an Ireland ester Claisen rearrangement and RCM reaction based strategy has been accomplished.

Subjects :: Claisen rearrangement
Bioactive metabolite
chemistry
Acremonium sp
Stereochemistry
Organic Chemistry
Drug Discovery
Total synthesis
chemistry.chemical_element
Spirobenzofuran
Biochemistry
Carbon

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