High Dose Intravenous Human IgG in the Treatment of Idiopathic Membranous Nephropathy: Preliminary Report of a Multicentric Trial

Twenty six adult patients were treated with high dose intravenous immuneglobulin (Endobulin-Immuno) for idiopathic membranous nephropathy and nephrotic syndrome.Pulse doses of 0.4 g/Kg b. wt. for 3 consecutive days were given and repeated twice after 3 weeks. Afterwards, one pulse dose every 3 weeks has been administered for a 12 months period. At the end of the study, 11 patients had a complete remission (daily proteinuria