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Blood Pressure Change in Intrafascicular Vagal Activities
- Source :
- Journal of Shanghai Jiaotong University (Science). 26:47-54
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Baroreflex plays a significant role in modulating blood pressure for the human body. It is known that activation of the vagal nerve related to baroreflex can lead to reductions of blood pressure. However, how the vagal activities quantitatively relate with blood pressure can hardly be achieved. Here fine carbon nanotube yarn (CNTy) electrodes were adopted for recording intrafascicular vagal activities, synchronized with measurement of arterial blood pressure in a rat. Together with a novel algorithm, the results preliminarily quantified that there were six clusters of neural spikes within recorded vagal activities, and the number of individual vagal spikes correspondingly varied with blood pressure. Especially for Cluster 2, the neural activations decreased with arterial blood pressure increasing. This study can shed lights on the quantified neural mechanism underlying the control of vagal activities on blood pressure, and guide the vagal-nerve neuromodulation for treating hypertension.
- Subjects :
- medicine.medical_specialty
Multidisciplinary
Blood pressure change
business.industry
Vagal nerve
digestive, oral, and skin physiology
030204 cardiovascular system & hematology
Baroreflex
Neuromodulation (medicine)
03 medical and health sciences
0302 clinical medicine
Blood pressure
Internal medicine
Cardiology
medicine
Carbon nanotube yarn
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 19958188 and 10071172
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Journal of Shanghai Jiaotong University (Science)
- Accession number :
- edsair.doi...........05687869ef147b0480a0cfda433e309d