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Phase managed organic synthesis 3. Symmetrical anhydrides from carboxylic acids via polymer assisted reaction

Authors :
Zhi-dong Zhang
Wilmer K. Fife
Source :
Tetrahedron Letters. 27:4937-4940
Publication Year :
1986
Publisher :
Elsevier BV, 1986.

Abstract

Symmetrical anhydrides are produced quickly and in high yield by treating mixtures of a carboxylic acid and one-half equivalent thionyl chloride in dichloromethane with a solid-state copolymer of 4-vinylpyridine. This conversion is accomplished equally well in batch or column mode.

Details

ISSN :
00404039
Volume :
27
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........04986c61339b23de5ba756f5dc209eb5
Full Text :
https://doi.org/10.1016/s0040-4039(00)85101-1