Abstract P299: Longitudinal Study of Angiotensins in Normal and Preeclamptic Pregnancy

To address whether differential regulation of the renin-angiotensin system (RAS) occurs in preelampsia, we performed an extensive analysis of the time course of circulating and urinary profiles of the vasoconstrictor (Ang II) and the vasodilator [Ang-(1-7)] components in pregnant and preeclamptic women. Plasma and spot urine samples were collected prospectively from nulliparous normal pregnant (n=67) and preeclamptic (n=19) women between the ages of 18-40, at