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A Twin-Herbal Combination was found to have Cardio-Vascular Protection Effects after repeated RCTs on four groups of patients with Different Disease Background A Cross-Biostatical Study
- Source :
- Journal of Cardiovascular Medicine and Cardiology. :063-068
- Publication Year :
- 2021
- Publisher :
- Peertechz Publications Private Limited, 2021.
-
Abstract
- Background and Objective: To perform an integrated Cross-Biostatical analysis of four randomized controlled trials (RCTs) to assess the efficacy and safety of oral administration of D&G capsule (D&G) for the maintenance of cardiovascular health. Methods: Data from the populations of four completed RCTs were pooled for this integrated Cross-Biostatical analysis. Mean changes from baseline in IMT and lipid profile were the main lines of attention; treatment differences were compared between D&G and Placebo groups. Primary outcome was Carotid artery intima-media thickness (IMT). Secondary outcome was the lipid profile. Analyses included primary and secondary outcome measures repeated at individual time points. Results: The pooled RCT data involved 453 subjects (245 DG 208 Placebo); demographic characteristics were similar between treatment groups. Taking all 4 groups together, the mean improvements in IMT from baseline to week 24 were 0.9163 to 0.8939 in D&G group, and 0.8997 to 0.8964 in Placebo group. A statistically significant improvement after treatment was observed (P
Details
- ISSN :
- 24552976
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Medicine and Cardiology
- Accession number :
- edsair.doi...........0357df00918bc974e40e54aa26f47c77