Discoid lupus erythematosus occurring in an area previously affected by herpes zoster virus: Wolf's isotopic reaction?

Cutaneous areas previously affected by herpes viruses appear to become predisposed to the subsequent development of a range of other unrelated conditions. We describe here a case of discoid lupus erythematosus (DLE), possibly triggered by an episode of shingles that had occurred in the same area (ophthalmic branch of the left trigeminal nerve), a few weeks before.A Caucasian man in his early 70s presented with a three-week history of a persistent erythematous, crusty and focally excoriated eruption, [...]