Back to Search
Start Over
ChemInform Abstract: A Facile Synthesis of 9-Nor-9-hydroxyhexahydrocannabinol via Intramolecular Reverse Electron Demand Diels-Alder Cyclization
- Source :
- ChemInform. 23
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- A simple and efficient new synthesis of 9-nor-9-hydroxyhexahydrocannabinol is achieved, through the intramolecular [4+2] cycloaddition of an o-quinonemethide which is generated from 2-(1-hydroxy-3-methoxymethoxy-7-methyl-6-octenyl)-1,3-bis(O-methoxymethyl)olivetol (12b), which in turn is prepared by reaction of the lithiated olivetol bis(methoxymethyl)ether with 3-methoxymethoxy-7-methyl-6-octenal (9)
Details
- ISSN :
- 09317597
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........02eab1fafa37677ec5216c7f50b6d906