ISS_Model

This is supplemental material for the article, "Estimating Insulin Sensitivity and Beta-Cell Function from the Oral Glucose Tolerance Test: Validation of a new Insulin Sensitivity and Secretion (ISS) Model", bioRxiv doi: https://doi.org/10.1101/2023.06.16.545377 Items: 1. Supplemental Table S1 2. Supplemental Figures S1 - S8 3. Supplemental Methods 4. Supplemental Equations 5. Supplemental Computer Code (Fitting_Code.zip) Run the Matlab script OGTT_fit.m, which calls OGTT_cost_function_universal.m and GI_ode_universal.m. It will read in the synthetic data Synthetic_Data.xlsx and output the fits to Synthetic_Fits.xlsx. The parameters are set to those used in the paper, but can be customized as desired.