Quantification of Actin Filament Organization by Estimating Graph Structures in Confocal Microscopic Images

With the progress in implant technology, the understanding of the interaction between implants and living cells and tissue raised in relevance. To get insight into the biocomplexity of the underlying cellular mechanisms in the cell-biomaterial dialogue, an automatic quantification of cell parameters is required as a first step. An ad hoc designed texture analysis procedure is implemented to assess the development of actin filaments in human osteoblasts grown on titanium surfaces from confocal microscopic images.