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Influence of PM1 exposure on total and cause-specific respiratory diseases: a systematic review and meta-analysis
- Source :
- Environmental Science and Pollution Research. 29:15117-15126
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- An increasing number of studies examined the potential effects of PM1 (submicronic particulate matter with an aerodynamic diameter ≤ 1 μm) on the risk of respiratory diseases; however, the results have been inconclusive. This study aimed to determine the overall association between PM1 with total and cause-specific respiratory diseases. A systematic review and meta-analysis was conducted with 68 related articles retrieved, and six articles met the full inclusion criteria for the final analysis. For a 10 μg/m3 increase in PM1, the pooled odds ratio (OR) was 1.05 (95% CI 0.98–1.12) for total respiratory diseases, 1.25 (95% CI 1.00–1.56) for asthma, and 1.07 (95% CI 1.04–1.10) for pneumonia with the I2 value of 87%, 70%, and 0%, respectively. Subgroup analyses showed that long-term exposure to PM1 was associated with increased risk of asthma (OR 1.47, 95% CI 1.33–1.63) with an I2 value of 0%, while short-term exposure to PM1 was not associated with asthma (OR 1.07, 95% CI 0.89–1.27) with the I2 value of 0%. Egger’s test showed that publication bias existed (P = 0.041); however, the funnel plot was symmetrical with the inclusion of the moderator. In conclusion, elevated levels of PM1 may increase morbidity in total and cause-specific respiratory diseases in the population.
- Subjects :
- medicine.medical_specialty
education.field_of_study
Funnel plot
business.industry
Health, Toxicology and Mutagenesis
Respiratory disease
Population
General Medicine
Publication bias
Odds ratio
medicine.disease
Pollution
Internal medicine
Meta-analysis
medicine
Environmental Chemistry
Respiratory system
business
education
Asthma
Subjects
Details
- ISSN :
- 16147499 and 09441344
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Environmental Science and Pollution Research
- Accession number :
- edsair.doi...........01fc5ef3050e69d0d5480b4835dc2245