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Portal vein thrombosis in cirrhotic and non cirrhotic patients: from diagnosis to treatment
- Source :
- Expert Opinion on Orphan Drugs. 4:927-940
- Publication Year :
- 2016
- Publisher :
- Informa UK Limited, 2016.
-
Abstract
- Introduction: Portal vein thrombosis (PVT) may occur in non-cirrhotic and cirrhotic patients. It can be classified as acute (if a recent thrombus is present) and chronic (if portal cavernoma has developed). Patients can be symptomatic or may present signs and symptoms related to the development of portal hypertension. In rare cases bowel infarction may occur.Areas covered: This review provides an overview of the clinical presentation, complications, diagnostic challenges and available treatments for PVT in non-cirrhotic and cirrhotic patients (NCPVT).Expert opinion: Treatment of acute NCPVT aims at recanalizing the thrombosed veins and preventing intestinal infarction and portal hypertension. Anticoagulation should be started promptly and maintained for at least 6 months. Long-term anticoagulation should be implemented in the presence of underlying persistent thrombotic state. In chronic NCPVT, treatment aims at managing portal hypertension and portal cavernoma cholangiopathy and preventing new th...
- Subjects :
- medicine.medical_specialty
Bowel infarction
business.industry
Health Policy
Portal venous pressure
Signs and symptoms
medicine.disease
Gastroenterology
Surgery
Portal vein thrombosis
03 medical and health sciences
Portal thrombosis
0302 clinical medicine
030220 oncology & carcinogenesis
Internal medicine
Intestinal infarction
Recent thrombus
medicine
Portal hypertension
030211 gastroenterology & hepatology
Pharmacology (medical)
business
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Subjects
Details
- ISSN :
- 21678707
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- Expert Opinion on Orphan Drugs
- Accession number :
- edsair.doi...........01deee6785edc81d3be468d097052705