CARDIOVASCULAR SIGNALING PROTEINS AS PREDICTORS OF DOXORUBICIN-RELATED CARDIAC EFFECTS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Authors :: Brent Anderson
Traci M. Blonquist
Uma H. Athale
Vivian I. Franco
Caroline Laverdière
Stephen E. Sallan
Barbara L. Asselin
Steven E. Lipshultz
Holly M. Smith
Marshall A. Schorin
Steven D. Colan
Donna S. Neuberg
Emma R. Lipshultz
Lewis B. Silverman
Bruno Michon
Luis A. Clavell
Neha Bansal
Tracie L. Miller
Rebecca E. Scully
Douglas Sawyer
Source :: Journal of the American College of Cardiology. 71:A927
Publication Year :: 2018
Publisher :: Elsevier BV, 2018.
Abstract: Cardiac signaling proteins regulate the intrinsic cardioprotective and repair response to doxorubicin cardiotoxicity. We estimated the relationship between these proteins, serum biomarkers of cardiac status and imaging in doxorubicin-treated children with ALL. Concentrations of the proteins

Subjects :: business.industry
Lymphoblastic Leukemia
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Serum biomarkers
030220 oncology & carcinogenesis
Signaling proteins
polycyclic compounds
cardiovascular system
Cancer research
Medicine
Doxorubicin
Cardiology and Cardiovascular Medicine
business
Doxorubicin cardiotoxicity
Cardiac status
medicine.drug

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