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Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation
- Source :
- Journal of Allergy and Clinical Immunology. 143:2202-2214.e5
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Objective: We set out to examine PG production in human ILC2s and the implications of such endogenous production on ILC2 function. Methods: The effects of the COX-1/2 inhibitor flurbiprofen, the he ...
- Subjects :
- 0301 basic medicine
Leukotriene
Thymic stromal lymphopoietin
Chemistry
medicine.medical_treatment
Immunology
Innate lymphoid cell
Flurbiprofen
Prostaglandin
Endogeny
Cell biology
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
0302 clinical medicine
Cytokine
medicine
Immunology and Allergy
Prostaglandin D2
030215 immunology
medicine.drug
Subjects
Details
- ISSN :
- 00916749
- Volume :
- 143
- Database :
- OpenAIRE
- Journal :
- Journal of Allergy and Clinical Immunology
- Accession number :
- edsair.doi...........01865469b2f24ec57464bf5be9ae7337
- Full Text :
- https://doi.org/10.1016/j.jaci.2018.10.069