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18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Assessing Tumor Response to Immunotherapy in Solid Tumors
- Source :
- PET Clinics. 15:11-22
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- The complexity of the immune response and diversity of targets challenges conventional conceptual frameworks used in selecting and monitoring treatment with immune check-point inhibitors. The limitations of anatomic imaging in assessing response have been recognized. Varying patterns of response have been recognized. These patterns have different implications for the continuation and duration of therapy. Evidence supporting the role of 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography as a prognostic biomarker and in characterizing response is presented. An added benefit of this approach is the ability to detect immune-related inflammatory reactions, often in advance of severe or life-threatening clinical manifestations.
- Subjects :
- PET-CT
medicine.medical_specialty
Radiation
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Melanoma
Cancer
Computed tomography
General Medicine
Immunotherapy
medicine.disease
030218 nuclear medicine & medical imaging
Fluorodeoxyglucose positron emission tomography
03 medical and health sciences
0302 clinical medicine
Positron emission tomography
030220 oncology & carcinogenesis
medicine
Medical imaging
Radiology, Nuclear Medicine and imaging
Radiology
business
Subjects
Details
- ISSN :
- 15568598
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- PET Clinics
- Accession number :
- edsair.doi...........01621b759f765c2e7a988746b8da1492