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Differential diagnosis of T2 hypointense masses in musculoskeletal MRI

Authors :
Adam D. Singer
Paul D. Clifford
Gregory B. Foremny
Juan Pretell-Mazzini
Dara Finkelstein
Ty K. Subhawong
Darcy A. Kerr
Source :
Skeletal Radiology. 50:1981-1994
Publication Year :
2021
Publisher :
Springer Science and Business Media LLC, 2021.

Abstract

Many soft tissue masses have an indeterminate appearance on MRI, often displaying varying degrees and extent of T2 hyperintensity. However, a subset of neoplasms and tumor-like lesions may exhibit prominent areas of T2 hypointensity relative to skeletal muscle. The hypointensity observed on T2-weighted MRI can be caused by a variety of substances, including evolving blood products, calcifications or other inorganic crystals, or fibrous tissue. Carefully evaluating the presence and pattern of T2 hypointensity in soft tissue masses and considering potential causes in their associated clinical contexts can help to narrow the differential diagnosis among neoplastic and non-neoplastic possibilities. These include endometriosis, aneurysmal bone cysts, tenosynovial giant cell tumor, arteriovenous malformation and pseudoaneurysm, calcium pyrophosphate and hydroxyapatite deposition diseases, tumoral calcinosis, gout, amyloidosis, hemangiomas with phleboliths, low-grade fibromyxoid sarcoma, ossifying fibromyxoid tumor, collagenous fibroma, desmoid-type fibromatosis, myxofibrosarcoma, peripheral nerve sheath tumors, dedifferentiated liposarcoma, and treated sarcoma.

Details

ISSN :
14322161 and 03642348
Volume :
50
Database :
OpenAIRE
Journal :
Skeletal Radiology
Accession number :
edsair.doi...........00887946e08cd870d03b873d095abd39
Full Text :
https://doi.org/10.1007/s00256-021-03711-0