P4-471: AMYLOID-β PLAQUE FORMATION AND REACTIVE GLIOSIS ARE REQUIRED FOR INDUCTION OF COGNITIVE DEFICITS AND SYNAPTIC DEGENERATION IN APP KNOCK-IN MOUSE MODELS OF ALZHEIMER'S DISEASE

Authors :: Michiko Sekiya
Takashi Saito
Takaomi C. Saido
Koichi M. Iijima
Yasufumi Sakakibara
Source :: Alzheimer's & Dementia. 15:P1492-P1492
Publication Year :: 2019
Publisher :: Wiley, 2019.

Subjects :: Amyloid β
Epidemiology
business.industry
Reactive gliosis
Health Policy
Cognition
Disease
Degeneration (medical)
Psychiatry and Mental health
Cellular and Molecular Neuroscience
Developmental Neuroscience
Medicine
Neurology (clinical)
Geriatrics and Gerontology
Knock in mouse
business
Neuroscience

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