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Induction of Probiotic Strain Enterococcus faecium EF1 on the Production of Cytokines, Superoxide Anion and Prostaglandin E2 in a Macrophage Cell Line

Authors :
Wei-fen Li, Qin Huang, Ya-li Li, Imran Rashid Rajput, Yi Huang§ and Cai-hong Hu
Source :
Pakistan Veterinary Journal, Vol 32, Iss 4, Pp 530-534 (2012)
Publication Year :
2012
Publisher :
University of Agriculture, Faisalabad, 2012.

Abstract

Immunological effects of probiotic strain Enterococcus faecium EF1 was evaluated through the production of cytokines, superoxide anion (O2.-) and prostaglandin E2 (PGE2) in murine macrophage cell line RAW 264.7. In addition, the responses were contrasted with a pathogenic coliform, Escherichia coli strain K88. After 12-h co-incubation of RAW 264.7 with E. faecium EF1 or E. coli K88, the culture supernatants were collected for further analysis of cytokines (TNF-α, IFN-γ, IL-1β, IL-6, IL-12, IL-8 and IL-10) and inflammatory mediators including superoxide anion (O2.-) and PGE2. The results showed that, E. faecium EF1 induced an increased (P

Details

Language :
English
ISSN :
02538318
Volume :
32
Issue :
4
Database :
OpenAIRE
Journal :
Pakistan Veterinary Journal
Accession number :
edsair.doajarticles..b9bd88f60796ba5b0d356fb006e35a99