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Combined vitrectomy, near-confluent panretinal endolaser, bevacizumab and cyclophotocoagulation for neovascular glaucoma — a retrospective interventional case series [version 2; peer review: 2 approved]
- Source :
- F1000Research, Vol 9 (2021)
- Publication Year :
- 2021
- Publisher :
- F1000 Research Ltd, 2021.
-
Abstract
- Background: Neovascular glaucoma (NVG) is a severe, potentially blinding disease and a therapeutic challenge. The purpose of this study was to evaluate the safety and efficacy of an integrative surgical approach to neovascular glaucoma. Methods: Retrospective analysis of a one-year follow-up of a consecutive interventional case series of NVG. Eyes underwent transscleral cyclophotocoagulation, pars plana vitrectomy, near-confluent panretinal photocoagulation, and intravitreal bevacizumab. Phakic eyes underwent concomitant cataract surgery. Best-corrected visual acuity (BCVA, logMAR), intraocular pressure (IOP, mmHg), number of glaucoma medication, visual analog pain scale (VAPS, 0-10) were recorded at baseline, and 1, 3, 6, and 12 months. Blind eyes were excluded. Results: Seventy-seven eyes of 77 patients (45 male, 32 female, mean age 73.6±12.2 years) were included. NVG underlying conditions included retinal vein occlusion (41.6%), proliferative diabetic retinopathy (35.1%), central retinal artery occlusion (19.5%), and ocular ischemic syndrome (3.9%). Mean IOP decreased postoperatively from 46.3±10.1 mmHg to 14.5±7.9 mmHg (p
- Subjects :
- genetic structures
lcsh:R
lcsh:Medicine
lcsh:Q
sense organs
lcsh:Science
eye diseases
Subjects
Details
- Language :
- English
- ISSN :
- 20461402
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- F1000Research
- Accession number :
- edsair.doajarticles..ab0fc160953e85f1e5e63eff66bd29b8