Proton Interaction Vertex Imaging for carbon therapy quality control

International audience; Purpose: In the framework of the 12C based hadrontherapy, the monitoring of the ion range is a crucial issue for the quality control of the treatments. An emerging method to perform a real-time monitoring exploits secondary charged particle radiation. Simulations have shown that the number of emerging protons is enough to perform ion-range monitoring in homogeneous targets on a pencil-beam basis operating in active mode. The variation of vertex distributions have been recently confirmed by an experiment performed with clinical beam and a PMMA target. The present study aims at comparing simulations and measurements obtained with homogeneous and heterogeneous target.