Back to Search Start Over

Biallelic SCN10A mutations in neuromuscular disease and epileptic encephalopathy

Authors :
Marios , Kambouris
Thevenon , Julien
Cox , Allison
Masurel-Paulet , Alice
Saint-Onge , Judith
Duffourd , Yannis
Chantegret , Corine
Thauvin-Robinet , Christel
El‐Shanti , Hatem
Faivre , Laurence
Riviere , Jean-Baptiste
Yale University School of Medicine
Yale School of Medicine
Centre de génétique - Centre de référence des maladies rares, anomalies du développement et syndromes malformatifs (CHU de Dijon)
Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon )
University of Iowa [Iowa]
Génétique des Anomalies du Développement ( GAD )
IFR100 - Structure fédérative de recherche Santé-STIC-Université de Bourgogne ( UB )
Qatar National Research Fund (QNRF) NPRP grant 09‐367‐3‐087 (MK and HE) and NPRP grant 6‐359‐3‐095 (HE and AGB)Shafallah Center Foundation, Doha, Qatar
Source :
Annals of Clinical and Translational Neurology, Annals of Clinical and Translational Neurology, Wiley, 2017, 4 (1), pp.26-35. 〈www.wiley.com〉. 〈10.1002/acn3.372〉, www.wiley.com
Publication Year :
2017
Publisher :
HAL CCSD, 2017.

Abstract

International audience; Two consanguineous families, one of Sudanese ethnicity presenting progressive neuromuscular disease, severe cognitive impairment, muscle weakness, upper motor neuron lesion, anhydrosis, facial dysmorphism, and recurrent seizures and the other of Egyptian ethnicity presenting with neonatal hypotonia, bradycardia, and recurrent seizures, were evaluated for the causative gene mutation.

Details

Language :
English
ISSN :
23289503
Database :
OpenAIRE
Journal :
Annals of Clinical and Translational Neurology, Annals of Clinical and Translational Neurology, Wiley, 2017, 4 (1), pp.26-35. 〈www.wiley.com〉. 〈10.1002/acn3.372〉, www.wiley.com
Accession number :
edsair.dedup.wf.001..b101ba206a6bca7a2d5bf5b1848f62f4
Full Text :
https://doi.org/10.1002/acn3.372〉