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From a Sequential Chemo-Enzymatic Approach to a Continuous Process for HMF Production from Glucose
- Source :
- Catalysts, Catalysts, MDPI, 2018, 8 (8), pp.335. ⟨10.3390/catal8080335⟩, Catalysts, 2018, 8 (8), pp.335. ⟨10.3390/catal8080335⟩, Catalysts, Vol 8, Iss 8, p 335 (2018), Volume 8, Issue 8
- Publication Year :
- 2018
- Publisher :
- HAL CCSD, 2018.
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Abstract
- International audience; Notably available from the cellulose contained in lignocellulosic biomass, glucose is a highly attractive substrate for eco-efficient processes towards high-value chemicals. A recent strategy for biomass valorization consists on combining biocatalysis and chemocatalysis to realise the so-called chemo-enzymatic or hybrid catalysis. Optimisation of the glucose conversion to 5-hydroxymethylfurfural (HMF) is the object of many research efforts. HMF can be produced by chemo-catalyzed fructose dehydration, while fructose can be selectively obtained from enzymatic glucose isomerization. Despite recent advances in HMF production, a fully integrated efficient process remains to be demonstrated. Our innovative approach consists on a continuous process involving enzymatic glucose isomerization, selective arylboronic-acid mediated fructose complexation/transportation, and chemical fructose dehydration to HMF. We designed a novel reactor based on two aqueous phases dynamically connected via an organic liquid membrane, which enabled substantial enhancement of glucose conversion (70%) while avoiding intermediate separation steps. Furthermore, in the as-combined steps, the use of an immobilized glucose isomerase and an acidic resin facilitates catalyst recycling
Details
- Language :
- English
- ISSN :
- 20734344
- Database :
- OpenAIRE
- Journal :
- Catalysts, Catalysts, MDPI, 2018, 8 (8), pp.335. ⟨10.3390/catal8080335⟩, Catalysts, 2018, 8 (8), pp.335. ⟨10.3390/catal8080335⟩, Catalysts, Vol 8, Iss 8, p 335 (2018), Volume 8, Issue 8
- Accession number :
- edsair.dedup.wf.001..b0a6be27476788296c1a5f8407d90a79