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Repeatability of Quantitative 18F-NaF PET: A Multicenter Study

Authors :
Boellaard, Ronald
Delgado-Bolton, Roberto
Oyen, Wim J.G.
Giammarile, Francesco
Tatsch, Klaus
Eschner, Wolfgang
Verzijlbergen, Fred J.
Barrington, Sally F.
Pike, Lucy C.
Weber, Wolfgang A.
Stroobants, Sigrid
Delbeke, Dominique
Donohoe, Kevin J.
Holbrook, Scott
Graham, Michael M.
Testanera, Giorgio
Hoekstra, Otto S.
Zijlstra, Josee
Visser, Eric
Hoekstra, Corneline J.
Pruim, Jan
Willemsen, Antoon
Arends, Bertjan
Kotzerke, J??rg
Bockisch, Andreas
Beyer, Thomas
Chiti, Arturo
Krause, Bernd J.
Brito, Ana E.
Santos, Allan
Sasse, André Deeke
Cabello, Cesar
Oliveira, Paulo
Mosci, Camila
Souza, Tiago
Amorim, Barbara
Lima, Mariana
Ramos, Celso D.
Etchebehere, Elba
Harmon, Stephanie A
Perk, Timothy
Lin, Chieh Christie
Eickhoff, Jens
Choyke, Peter L.
Dahut, William L.
Andrea, B
Humm, John L.
Larson, Steven M
Morris, Michael J.
Liu, Glenn
Jeraj, Robert
Bradshaw, T.
Jallow, N.
Perlman, S.
Apolo, A. B.
Itti, Emmanuel
Haioun, Corinne
Petegnief, Yolande
Luciani, Alain
Dupuis, Jehan
Paone, Gaetano
Talbot, Jean-Noël
Rahmouni, Alain
Meignan, Michel
Marinelli, Brett
Espinet-Col, Carina
Ulaner, Gary A
McArthur, Heather L
Gonen, Mithat
Jochelson, Maxine
Murray, Iain
Chittenden, Sarah J.
Denis-Bacelar, Ana M.
Hindorf, Cecilia
Parker, Christopher C.
Chua, Sue
Flux, Glenn D.
Radiology and nuclear medicine
CCA - Imaging and biomarkers
Hematology
Source :
Boellaard, R, Delgado-Bolton, R, Oyen, W J G, Giammarile, F, Tatsch, K, Eschner, W, Verzijlbergen, F J, Barrington, S F, Pike, L C, Weber, W A, Stroobants, S, Delbeke, D, Donohoe, K J, Holbrook, S, Graham, M M, Testanera, G, Hoekstra, O S, Zijlstra, J, Visser, E, Hoekstra, C J, Pruim, J, Willemsen, A, Arends, B, Kotzerke, J, Bockisch, A, Beyer, T, Chiti, A, Krause, B J, Brito, A E, Santos, A, Sasse, A D, Cabello, C, Oliveira, P, Mosci, C, Souza, T, Amorim, B, Lima, M, Ramos, C D, Etchebehere, E, Harmon, S A, Perk, T, Lin, C C, Eickhoff, J, Choyke, P L, Dahut, W L, Andrea, B, Humm, J L, Larson, S M, Morris, M J, Liu, G, Jeraj, R, Bradshaw, T, Perk, T, Harmon, S A, Eickhoff, J, Jallow, N, Choyke, P L, Dahut, W L, Larson, S M, Humm, J L, Perlman, S, Apolo, A B, Morris, M J, Liu, G, Jeraj, R, Itti, E, Haioun, C, Petegnief, Y, Luciani, A, Dupuis, J, Paone, G, Talbot, J-N, Rahmouni, A, Meignan, M, Marinelli, B, Espinet-Col, C, Ulaner, G A, McArthur, H L, Gonen, M, Jochelson, M, Weber, W A, Murray, I, Chittenden, S J, Denis-Bacelar, A M, Hindorf, C, Parker, C C, Chua, S & Flux, G D 2017, Repeatability of Quantitative 18F-NaF PET: A Multicenter Study . in European Journal of Nuclear Medicine and Molecular Imaging . European Journal of Nuclear Medicine and Molecular Imaging, vol. 57, European Journal of Nuclear Medicine and Molecular Imaging, pp. 328-354 . https://doi.org/10.2967/jnumed.116.177295, European Journal of Nuclear Medicine and Molecular Imaging, 328-354, STARTPAGE=328;ENDPAGE=354;TITLE=European Journal of Nuclear Medicine and Molecular Imaging
Publication Year :
2017
Publisher :
European Journal of Nuclear Medicine and Molecular Imaging, 2017.

Abstract

PURPOSE In bone-metastatic breast cancer patients, there are no current imaging biomarkers to identify which patients have worst prognosis. The purpose of our study was to investigate if skeletal tumor burden determined by 18F-Fluoride PET/CT correlates with clinical outcomes and may help define prognosis throughout the course of the disease. RESULTS Bone metastases were present in 49 patients. On multivariable analysis, skeletal tumor burden was significantly and independently associated with overall survival (p

Details

Language :
English
Database :
OpenAIRE
Journal :
Boellaard, R, Delgado-Bolton, R, Oyen, W J G, Giammarile, F, Tatsch, K, Eschner, W, Verzijlbergen, F J, Barrington, S F, Pike, L C, Weber, W A, Stroobants, S, Delbeke, D, Donohoe, K J, Holbrook, S, Graham, M M, Testanera, G, Hoekstra, O S, Zijlstra, J, Visser, E, Hoekstra, C J, Pruim, J, Willemsen, A, Arends, B, Kotzerke, J, Bockisch, A, Beyer, T, Chiti, A, Krause, B J, Brito, A E, Santos, A, Sasse, A D, Cabello, C, Oliveira, P, Mosci, C, Souza, T, Amorim, B, Lima, M, Ramos, C D, Etchebehere, E, Harmon, S A, Perk, T, Lin, C C, Eickhoff, J, Choyke, P L, Dahut, W L, Andrea, B, Humm, J L, Larson, S M, Morris, M J, Liu, G, Jeraj, R, Bradshaw, T, Perk, T, Harmon, S A, Eickhoff, J, Jallow, N, Choyke, P L, Dahut, W L, Larson, S M, Humm, J L, Perlman, S, Apolo, A B, Morris, M J, Liu, G, Jeraj, R, Itti, E, Haioun, C, Petegnief, Y, Luciani, A, Dupuis, J, Paone, G, Talbot, J-N, Rahmouni, A, Meignan, M, Marinelli, B, Espinet-Col, C, Ulaner, G A, McArthur, H L, Gonen, M, Jochelson, M, Weber, W A, Murray, I, Chittenden, S J, Denis-Bacelar, A M, Hindorf, C, Parker, C C, Chua, S & Flux, G D 2017, Repeatability of Quantitative 18F-NaF PET: A Multicenter Study . in European Journal of Nuclear Medicine and Molecular Imaging . European Journal of Nuclear Medicine and Molecular Imaging, vol. 57, European Journal of Nuclear Medicine and Molecular Imaging, pp. 328-354 . https://doi.org/10.2967/jnumed.116.177295, European Journal of Nuclear Medicine and Molecular Imaging, 328-354, STARTPAGE=328;ENDPAGE=354;TITLE=European Journal of Nuclear Medicine and Molecular Imaging
Accession number :
edsair.dedup.wf.001..9c84d654baaeb6479e18885d2f4ff145
Full Text :
https://doi.org/10.2967/jnumed.116.177295